Motif ID: NFY{A,B,C}.p2

Z-value: 4.032


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma



Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_538909 8.111 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr7_-_150305933 4.560 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr1_-_159257486 4.351 F11R
F11 receptor
chr7_-_71515295 4.220 NM_031468
CALN1
calneuron 1
chrX_+_47999740 4.216 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr7_+_129497808 4.204 KLHDC10
kelch domain containing 10
chr17_+_54587641 4.200 NM_018304
PRR11
proline rich 11
chr7_+_129497637 4.125 KLHDC10
kelch domain containing 10
chr7_+_129497572 3.987 NM_014997
KLHDC10
kelch domain containing 10
chr22_-_20419975 3.982 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr17_+_54587882 3.925 PRR11
proline rich 11
chr19_-_1992862 3.800 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr19_-_1993022 3.669 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_-_109742020 3.557 NM_002959
SORT1
sortilin 1
chr19_-_6375801 3.484 KHSRP
KH-type splicing regulatory protein
chr1_-_148868178 3.440 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chrX_+_49013243 3.423 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory (inhibitor) subunit 3F

chr21_+_39745649 3.361 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr14_-_22458220 3.267 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr17_-_54587581 3.208 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr1_-_159257567 3.197 F11R
F11 receptor
chr13_-_29938029 3.180 NM_002128
HMGB1
high-mobility group box 1
chr14_-_22458199 3.129 RBM23
RNA binding motif protein 23
chr14_+_28305922 3.077 NM_005249
FOXG1
forkhead box G1
chr19_+_50086362 3.055 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_+_42920729 2.999 YBX1
Y box binding protein 1
chr19_+_4920123 2.937 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr1_+_42920718 2.936 YBX1
Y box binding protein 1
chrX_+_49013270 2.934 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr1_+_42920755 2.924 YBX1
Y box binding protein 1
chr1_-_159257595 2.894 NM_016946
F11R
F11 receptor
chr22_-_22511173 2.889 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr7_-_156495985 2.887 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chrX_+_52797004 2.853 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chr14_-_22458134 2.808 RBM23
RNA binding motif protein 23
chr19_-_50840446 2.730 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr1_-_148868713 2.722 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr19_+_50086357 2.722 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr19_+_46462113 2.707 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr1_+_51968046 2.684 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr13_-_29937966 2.676 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr7_+_156496360 2.655 LOC645249
hypothetical LOC645249
chr1_+_42920692 2.639 YBX1
Y box binding protein 1
chr19_+_50086350 2.638 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr19_+_50086299 2.621 NM_001128916
NM_001128917
NM_006114
TOMM40


translocase of outer mitochondrial membrane 40 homolog (yeast)


chrX_+_49013424 2.609 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr5_+_150206277 2.607 NM_001145805
IRGM
immunity-related GTPase family, M
chr1_+_42920774 2.566 YBX1
Y box binding protein 1
chrX_+_22927998 2.566 NM_182699
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
chr1_+_42920685 2.542 YBX1
Y box binding protein 1
chr7_-_150306169 2.529 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_51968096 2.520 OSBPL9
oxysterol binding protein-like 9
chr11_+_13646806 2.513 FAR1
fatty acyl CoA reductase 1
chr11_+_61473931 2.505 NM_001139443
NM_004183
BEST1

bestrophin 1

chr19_-_6375804 2.500 KHSRP
KH-type splicing regulatory protein
chr21_+_44761927 2.499 C21orf90
chromosome 21 open reading frame 90
chr5_+_148717762 2.491 NM_024028
PCYOX1L
prenylcysteine oxidase 1 like
chr12_-_120725210 2.486 LOC338799
hypothetical LOC338799
chr11_-_64302440 2.485 SF1
splicing factor 1
chr19_-_12858956 2.484 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr1_-_148868671 2.478 ENSA
endosulfine alpha
chr22_-_21193037 2.446 ZNF280B
zinc finger protein 280B
chr19_-_6375782 2.444 KHSRP
KH-type splicing regulatory protein
chr1_+_51968191 2.441 OSBPL9
oxysterol binding protein-like 9
chr6_+_25834983 2.413 NM_170610
HIST1H2BA
histone cluster 1, H2ba
chr1_-_148868535 2.408 ENSA
endosulfine alpha
chr19_-_6375820 2.407 NM_003685
KHSRP
KH-type splicing regulatory protein
chr1_+_42920683 2.391 YBX1
Y box binding protein 1
chr1_-_23729871 2.374 E2F2
E2F transcription factor 2
chr19_+_45794895 2.355 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr1_-_151910080 2.323 ILF2
interleukin enhancer binding factor 2, 45kDa
chr18_-_43711143 2.298 SMAD2
SMAD family member 2
chr6_-_25834733 2.296 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr1_-_151910041 2.272 ILF2
interleukin enhancer binding factor 2, 45kDa
chr5_+_148717806 2.261 PCYOX1L
prenylcysteine oxidase 1 like
chr20_-_45418818 2.246 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chrX_-_100549444 2.244 GLA
galactosidase, alpha
chr21_-_39642935 2.233 HMGN1
high-mobility group nucleosome binding domain 1
chr21_-_39642712 2.210 HMGN1
high-mobility group nucleosome binding domain 1
chrX_+_48127911 2.194 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chrX_-_153016368 2.193 NM_001110792
NM_004992
MECP2

methyl CpG binding protein 2 (Rett syndrome)

chr15_-_97368546 2.168 NM_001167902
PGPEP1L
pyroglutamyl-peptidase I-like
chr1_-_151910057 2.163 ILF2
interleukin enhancer binding factor 2, 45kDa
chr11_+_13646727 2.157 NM_032228
FAR1
fatty acyl CoA reductase 1
chr1_-_151910052 2.148 ILF2
interleukin enhancer binding factor 2, 45kDa
chr11_-_73371945 2.130 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_-_6375536 2.094 KHSRP
KH-type splicing regulatory protein
chr15_+_73278285 2.086 C15orf39
chromosome 15 open reading frame 39
chr8_-_103735194 2.066 NM_001032282
KLF10
Kruppel-like factor 10
chr19_+_50086405 2.063 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chrX_-_153016337 2.043 MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr3_-_187770790 2.029 TBCCD1
TBCC domain containing 1
chr6_+_99389318 2.021 POU3F2
POU class 3 homeobox 2
chr11_-_4585947 2.019 NM_018073
TRIM68
tripartite motif containing 68
chr6_-_30792830 2.019 MDC1
mediator of DNA-damage checkpoint 1
chr19_+_46462125 2.006 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr3_+_37009987 2.005 MLH1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr17_-_77411607 1.996 P4HB
prolyl 4-hydroxylase, beta polypeptide
chrX_+_70420237 1.996 NONO
non-POU domain containing, octamer-binding
chr6_+_99389300 1.982 NM_005604
POU3F2
POU class 3 homeobox 2
chr6_-_33393696 1.980 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr6_-_31890765 1.971 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chrX_-_153016173 1.966 MECP2
LOC728653
methyl CpG binding protein 2 (Rett syndrome)
hypothetical protein LOC728653
chr11_-_64302509 1.960 NM_001178030
SF1
splicing factor 1
chr19_+_46462189 1.954 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_-_64302564 1.952 SF1
splicing factor 1
chr19_+_46462169 1.951 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr17_-_77411733 1.926 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr1_-_52116598 1.917 NRD1
nardilysin (N-arginine dibasic convertase)
chr19_-_54350457 1.916 NM_002152
HRC
histidine rich calcium binding protein
chr19_+_46462176 1.915 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chrX_+_70420259 1.906 NONO
non-POU domain containing, octamer-binding
chr11_+_13646822 1.898 FAR1
fatty acyl CoA reductase 1
chr21_-_39642880 1.894 NM_004965
HMGN1
high-mobility group nucleosome binding domain 1
chr19_+_55398680 1.894 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chrX_+_70420221 1.892 NONO
non-POU domain containing, octamer-binding
chr9_-_139084833 1.888 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr9_-_94095734 1.886 IARS
isoleucyl-tRNA synthetase
chr1_-_171838802 1.885 NM_178527
SLC9A11
solute carrier family 9, member 11
chr1_+_24158887 1.884 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chrX_-_77037563 1.866 NM_032121
MAGT1
magnesium transporter 1
chr17_-_73694669 1.858 NM_003258
TK1
thymidine kinase 1, soluble
chr1_+_42920889 1.849 YBX1
Y box binding protein 1
chr1_-_148868664 1.829 ENSA
endosulfine alpha
chrX_+_70420194 1.818 NONO
non-POU domain containing, octamer-binding
chr1_+_24158898 1.817 PNRC2
proline-rich nuclear receptor coactivator 2
chr5_-_150118274 1.812 NM_001135644
DCTN4
dynactin 4 (p62)
chr21_-_39642808 1.800 HMGN1
high-mobility group nucleosome binding domain 1
chr1_-_195382189 1.791 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_-_187771025 1.791 NM_001134415
TBCCD1
TBCC domain containing 1
chr5_+_70918935 1.788 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_+_43888391 1.788 KDM4A
lysine (K)-specific demethylase 4A
chr1_-_89511065 1.784 NM_001134486
NM_052942
GBP5

guanylate binding protein 5

chr19_-_17377383 1.777 NM_004335
BST2
bone marrow stromal cell antigen 2
chr5_+_70918893 1.772 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr17_+_73694992 1.766 NM_001010982
NM_001145526
AFMID

arylformamidase

chr1_-_148868644 1.765 ENSA
endosulfine alpha
chrX_+_46889563 1.763 NM_005676
NM_152856
RBM10

RNA binding motif protein 10

chr1_+_246167115 1.756 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr19_+_54961880 1.750 NM_014203
NM_130787
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr1_-_28113540 1.750 RPA2
replication protein A2, 32kDa
chr7_+_98940801 1.743 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr17_-_77411695 1.732 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr5_+_70918888 1.729 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chrX_+_100549869 1.727 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_+_100549885 1.724 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_-_157313179 1.723 NM_004833
AIM2
absent in melanoma 2
chr1_+_43888415 1.719 KDM4A
lysine (K)-specific demethylase 4A
chr1_-_149586298 1.709 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr12_-_55013987 1.706 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr7_-_44854092 1.704 H2AFV
H2A histone family, member V
chr1_+_159741824 1.704 NM_001136219
NM_021642
FCGR2A

Fc fragment of IgG, low affinity IIa, receptor (CD32)

chr1_+_165225121 1.698 NM_032858
MAEL
maelstrom homolog (Drosophila)
chr5_+_70918856 1.690 NM_022132
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_-_46370837 1.688 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr22_+_20316968 1.687 NM_152612
CCDC116
coiled-coil domain containing 116
chr17_-_77411659 1.685 P4HB
prolyl 4-hydroxylase, beta polypeptide
chrX_-_100549561 1.680 NM_000169
GLA
galactosidase, alpha
chrX_-_106336199 1.665 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr19_+_1442000 1.665 NM_138393
REEP6
receptor accessory protein 6
chr12_+_112143670 1.649 TPCN1
two pore segment channel 1
chr22_+_17847467 1.647 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr16_+_166678 1.645 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr11_+_13646839 1.637 FAR1
fatty acyl CoA reductase 1
chr1_+_5975345 1.637 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr14_+_23711044 1.629 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr16_+_162845 1.626 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr6_+_33151703 1.608 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr19_-_45948211 1.602 C19orf54
chromosome 19 open reading frame 54
chrX_+_100549839 1.598 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chr9_-_35804982 1.595


chr15_+_74416156 1.593 NM_145805
ISL2
ISL LIM homeobox 2
chr9_-_126945536 1.589 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr1_-_148936123 1.588 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr19_+_4920126 1.586 KDM4B
lysine (K)-specific demethylase 4B
chr19_-_45948189 1.586 C19orf54
chromosome 19 open reading frame 54
chr16_+_1772929 1.585 NM_012225
NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr12_+_112143658 1.581 TPCN1
two pore segment channel 1
chrX_-_48101044 1.578 NM_021014
NM_175711
SSX3

synovial sarcoma, X breakpoint 3

chr1_+_42920635 1.574 NM_004559
YBX1
Y box binding protein 1
chrX_-_47394808 1.570 ELK1
ELK1, member of ETS oncogene family
chr12_-_55013713 1.569 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr7_-_135063461 1.567 NM_012450
SLC13A4
solute carrier family 13 (sodium/sulfate symporters), member 4
chrX_+_46889614 1.567 RBM10
RNA binding motif protein 10
chr18_-_43711452 1.563 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr1_+_43888382 1.562 NM_014663
KDM4A
lysine (K)-specific demethylase 4A
chr15_+_78139073 1.560 NM_019006
ZFAND6
zinc finger, AN1-type domain 6
chr11_-_64302720 1.553 SF1
splicing factor 1
chr22_+_17847413 1.545 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chrX_-_47394937 1.543 NM_001114123
NM_005229
ELK1

ELK1, member of ETS oncogene family

chr7_+_98940508 1.539 NM_014569
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr3_+_187771139 1.539 NM_016306
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr12_-_53065758 1.534 ZNF385A
zinc finger protein 385A
chr12_+_6473552 1.531 NM_014865
NCAPD2
non-SMC condensin I complex, subunit D2
chrX_+_100549861 1.526 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_+_46889620 1.524 RBM10
RNA binding motif protein 10
chr3_-_161766055 1.520 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr19_+_60543032 1.520 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr14_-_63178287 1.505 NM_080666
WDR89
WD repeat domain 89
chr16_+_1773004 1.503 NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.39 2.14e-21 GO:0022403 cell cycle phase
2.77 1.25e-20 GO:0000279 M phase
2.40 2.51e-19 GO:0051276 chromosome organization
2.03 7.19e-19 GO:0007049 cell cycle
2.18 8.28e-19 GO:0022402 cell cycle process
2.40 5.70e-18 GO:0000278 mitotic cell cycle
1.77 8.88e-18 GO:0006996 organelle organization
2.89 8.36e-16 GO:0000087 M phase of mitotic cell cycle
1.37 6.02e-15 GO:0044260 cellular macromolecule metabolic process
3.86 2.27e-14 GO:0006323 DNA packaging
3.59 4.59e-14 GO:0071103 DNA conformation change
2.79 9.57e-14 GO:0000280 nuclear division
2.79 9.57e-14 GO:0007067 mitosis
2.35 2.53e-13 GO:0006325 chromatin organization
4.05 2.83e-13 GO:0065004 protein-DNA complex assembly
3.93 5.10e-13 GO:0071824 protein-DNA complex subunit organization
3.07 5.79e-13 GO:0000075 cell cycle checkpoint
2.70 6.80e-13 GO:0048285 organelle fission
1.54 8.14e-13 GO:0090304 nucleic acid metabolic process
1.26 1.26e-12 GO:0044237 cellular metabolic process
2.56 1.26e-12 GO:0010564 regulation of cell cycle process
4.23 1.34e-12 GO:0006334 nucleosome assembly
4.02 2.17e-12 GO:0034728 nucleosome organization
3.53 3.03e-12 GO:0006333 chromatin assembly or disassembly
2.95 4.42e-12 GO:0071156 regulation of cell cycle arrest
4.01 1.11e-11 GO:0031497 chromatin assembly
2.08 1.61e-11 GO:0051726 regulation of cell cycle
1.44 6.10e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 6.54e-11 GO:0044238 primary metabolic process
1.29 2.43e-10 GO:0043170 macromolecule metabolic process
1.38 1.46e-09 GO:0034641 cellular nitrogen compound metabolic process
1.20 3.07e-09 GO:0008152 metabolic process
1.36 3.83e-09 GO:0006807 nitrogen compound metabolic process
1.43 5.41e-09 GO:0009058 biosynthetic process
1.40 7.36e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.41 7.54e-09 GO:0071842 cellular component organization at cellular level
1.43 8.02e-09 GO:0044249 cellular biosynthetic process
2.28 1.99e-08 GO:0051301 cell division
1.11 4.22e-08 GO:0009987 cellular process
3.39 8.26e-08 GO:0007059 chromosome segregation
1.50 2.18e-07 GO:0034645 cellular macromolecule biosynthetic process
1.49 3.99e-07 GO:0009059 macromolecule biosynthetic process
1.31 2.40e-06 GO:0016043 cellular component organization
2.21 2.74e-06 GO:0051325 interphase
1.84 3.46e-06 GO:0006259 DNA metabolic process
1.30 3.48e-06 GO:0071840 cellular component organization or biogenesis
2.21 3.49e-06 GO:0051329 interphase of mitotic cell cycle
1.44 9.30e-06 GO:0016070 RNA metabolic process
1.65 2.69e-05 GO:0033554 cellular response to stress
3.28 3.38e-05 GO:0000236 mitotic prometaphase
4.89 4.77e-05 GO:0006695 cholesterol biosynthetic process
1.98 8.09e-05 GO:0034622 cellular macromolecular complex assembly
2.14 1.18e-04 GO:0007346 regulation of mitotic cell cycle
4.40 1.26e-04 GO:0016126 sterol biosynthetic process
2.39 1.51e-04 GO:0006260 DNA replication
4.03 2.53e-04 GO:0000819 sister chromatid segregation
2.29 3.00e-04 GO:0006457 protein folding
1.97 3.13e-04 GO:0006281 DNA repair
1.64 4.90e-04 GO:0065003 macromolecular complex assembly
1.37 5.46e-04 GO:0010467 gene expression
1.76 5.88e-04 GO:0006974 response to DNA damage stimulus
2.60 7.51e-04 GO:0007093 mitotic cell cycle checkpoint
1.90 8.38e-04 GO:0016568 chromatin modification
1.30 8.43e-04 GO:0044267 cellular protein metabolic process
1.24 8.68e-04 GO:0031323 regulation of cellular metabolic process
1.31 1.04e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.24 1.31e-03 GO:0080090 regulation of primary metabolic process
2.68 1.35e-03 GO:0007126 meiosis
2.68 1.35e-03 GO:0051327 M phase of meiotic cell cycle
2.66 1.66e-03 GO:0051321 meiotic cell cycle
2.47 1.90e-03 GO:0006310 DNA recombination
1.74 1.99e-03 GO:0034621 cellular macromolecular complex subunit organization
3.84 2.87e-03 GO:0000070 mitotic sister chromatid segregation
1.27 3.06e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.24 4.06e-03 GO:0060255 regulation of macromolecule metabolic process
1.27 4.32e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 4.37e-03 GO:0019222 regulation of metabolic process
1.31 4.85e-03 GO:0006355 regulation of transcription, DNA-dependent
2.82 5.06e-03 GO:0018196 peptidyl-asparagine modification
2.82 5.06e-03 GO:0018279 protein N-linked glycosylation via asparagine
2.74 5.32e-03 GO:0006487 protein N-linked glycosylation
1.52 5.72e-03 GO:0043933 macromolecular complex subunit organization
1.28 7.09e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.29 8.10e-03 GO:0051252 regulation of RNA metabolic process
3.24 1.09e-02 GO:0007127 meiosis I
1.26 1.17e-02 GO:0031326 regulation of cellular biosynthetic process
2.23 1.52e-02 GO:0010498 proteasomal protein catabolic process
2.23 1.52e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.25 1.58e-02 GO:0009889 regulation of biosynthetic process
1.26 1.60e-02 GO:0010468 regulation of gene expression
1.71 1.63e-02 GO:0044262 cellular carbohydrate metabolic process
1.31 1.71e-02 GO:0043412 macromolecule modification
1.64 2.06e-02 GO:0044265 cellular macromolecule catabolic process
1.41 2.12e-02 GO:0044085 cellular component biogenesis
7.06 2.27e-02 GO:0000085 G2 phase of mitotic cell cycle
7.06 2.27e-02 GO:0051319 G2 phase
5.34 2.78e-02 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
2.41 2.99e-02 GO:0031570 DNA integrity checkpoint
1.57 3.03e-02 GO:0009057 macromolecule catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.60e-47 GO:0043226 organelle
1.30 5.51e-47 GO:0043229 intracellular organelle
1.34 1.92e-46 GO:0043227 membrane-bounded organelle
1.34 4.64e-46 GO:0043231 intracellular membrane-bounded organelle
1.24 2.57e-45 GO:0044424 intracellular part
1.22 8.48e-43 GO:0005622 intracellular
1.48 6.36e-39 GO:0005634 nucleus
2.87 8.83e-32 GO:0005694 chromosome
1.43 1.71e-31 GO:0044422 organelle part
1.43 1.11e-30 GO:0044446 intracellular organelle part
2.98 2.13e-29 GO:0044427 chromosomal part
1.65 8.61e-21 GO:0070013 intracellular organelle lumen
1.66 5.20e-20 GO:0044428 nuclear part
3.33 7.19e-20 GO:0000785 chromatin
1.62 9.11e-20 GO:0031974 membrane-enclosed lumen
1.62 2.88e-19 GO:0043233 organelle lumen
1.47 5.88e-19 GO:0032991 macromolecular complex
1.54 2.47e-18 GO:0043228 non-membrane-bounded organelle
1.54 2.47e-18 GO:0043232 intracellular non-membrane-bounded organelle
1.21 5.10e-16 GO:0005737 cytoplasm
1.64 1.05e-15 GO:0031981 nuclear lumen
1.25 8.18e-12 GO:0044444 cytoplasmic part
2.83 2.60e-11 GO:0000228 nuclear chromosome
4.72 4.19e-11 GO:0000786 nucleosome
1.40 6.19e-11 GO:0043234 protein complex
3.03 8.10e-11 GO:0044454 nuclear chromosome part
3.24 1.42e-10 GO:0000793 condensed chromosome
3.74 2.63e-10 GO:0032993 protein-DNA complex
1.63 3.15e-10 GO:0005654 nucleoplasm
2.96 2.34e-08 GO:0000775 chromosome, centromeric region
1.81 4.82e-08 GO:0015630 microtubule cytoskeleton
4.22 2.51e-07 GO:0000794 condensed nuclear chromosome
3.06 3.03e-05 GO:0000776 kinetochore
1.04 4.54e-05 GO:0044464 cell part
1.04 4.71e-05 GO:0005623 cell
3.10 1.20e-04 GO:0000779 condensed chromosome, centromeric region
1.33 2.09e-04 GO:0005829 cytosol
2.23 3.91e-04 GO:0005819 spindle
6.48 5.16e-04 GO:0042613 MHC class II protein complex
3.04 5.58e-04 GO:0000777 condensed chromosome kinetochore
1.55 1.25e-03 GO:0044451 nucleoplasm part
1.65 2.08e-03 GO:0030529 ribonucleoprotein complex
2.71 4.62e-03 GO:0000790 nuclear chromatin
6.42 9.73e-03 GO:0000780 condensed nuclear chromosome, centromeric region
1.78 1.78e-02 GO:0005874 microtubule
3.21 2.47e-02 GO:0000792 heterochromatin
4.32 3.98e-02 GO:0000795 synaptonemal complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.45 4.21e-16 GO:0003676 nucleic acid binding
1.47 2.36e-11 GO:0003677 DNA binding
1.11 6.13e-10 GO:0005488 binding
1.18 2.28e-08 GO:0005515 protein binding
1.31 3.04e-04 GO:0000166 nucleotide binding
1.47 9.51e-04 GO:0030528 transcription regulator activity
3.69 2.91e-03 GO:0003678 DNA helicase activity
1.35 4.99e-03 GO:0005524 ATP binding
1.48 5.46e-03 GO:0003723 RNA binding
1.34 5.83e-03 GO:0030554 adenyl nucleotide binding
1.34 6.05e-03 GO:0032559 adenyl ribonucleotide binding
2.05 8.92e-03 GO:0003682 chromatin binding
3.90 1.38e-02 GO:0004003 ATP-dependent DNA helicase activity
3.01 1.58e-02 GO:0003697 single-stranded DNA binding
2.02 1.67e-02 GO:0043566 structure-specific DNA binding
2.84 2.21e-02 GO:0008094 DNA-dependent ATPase activity
1.40 2.29e-02 GO:0001071 nucleic acid binding transcription factor activity
1.40 2.29e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 3.57e-02 GO:0003824 catalytic activity
6.72 4.19e-02 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity